Synthesis, characterization and anti-fungal potential evaluation of 1, 4 thiazine derivatives by Mannich bases

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Synthesis and Biological Activity of Certain Mannich Bases Derivatives from 1, 2, 4-Triazoles

Substituted 1, 2, 4- Triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. These triazoles were used for preparation of different derivatives by two different schemes. In the first scheme the Mannich bases were prepared from 5- marcapto-s triazole Quinazolines. The 5-Marcato-s-Tr...

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15 صفحه اول

synthesis and biological activity of certain mannich bases derivatives from 1, 2, 4-triazoles

substituted 1, 2, 4- triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. these triazoles were used for preparation of different derivatives by two different schemes. in the first scheme the mannich bases were prepared from 5- marcapto-s triazole quinazolines. the 5-marcato-s-tr...

متن کامل

Synthesis and Biological Activity of Certain Mannich Bases Derivatives from 1, 2, 4-Triazoles

Substituted 1, 2, 4Triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. These triazoles were used for preparation of different derivatives by two different schemes. In the first scheme the Mannich bases were prepared from 5marcapto-s triazole Quinazolines. The 5-Marcato-s-Triazo...

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SYNTHESIS OF PARACETAMOL DERIVATIVES AS MANNICH BASES AND THEIR ANTIBACTERIAL ACTIVITY

Aim: A variety of Paracetamol derivatives as mannich bases were prepared through mannich reaction by reacting Paracetamol as compound containing active hydrogen, substituted benzaldehyde, morpholine as secondary amine compound and small amount of conc. HCl as catalyst. A simplistic one-pot method under mild conditions has been developed for the synthesis of all the compounds and they were chara...

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ژورنال

عنوان ژورنال: Hygeia journal for drugs and medicines

سال: 2018

ISSN: 0975-6221,2229-3590

DOI: 10.15254/h.j.d.med.10.2018.175